INT190017

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Context Info
Confidence 0.10
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 7.00
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Scrib) cell proliferation (Scrib) plasma membrane (Scrib)
cytoplasm (Scrib)
Anatomy Link Frequency
anterior 1
Scrib (Mus musculus)
Pain Link Frequency Relevance Heat
abdominal pain 1 83.24 Quite High
agonist 29 81.04 Quite High
Inflammation 82 78.60 Quite High
antagonist 2 57.80 Quite High
cytokine 5 42.60 Quite Low
cINOD 9 5.00 Very Low Very Low Very Low
Crohn's disease 7 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 267 100.00 Very High Very High Very High
Colon Cancer 203 100.00 Very High Very High Very High
Colorectal Cancer 146 100.00 Very High Very High Very High
Nicotine Addiction 3 99.50 Very High Very High Very High
Familial Adenomatous Polyposis 16 96.32 Very High Very High Very High
Inflammatory Bowel Disease 23 93.08 High High
Metastasis 46 92.96 High High
Malignant Neoplastic Disease 14 92.44 High High
Adenocarcinoma 9 90.92 High High
Pathologic Constriction 1 86.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
mutation in CRC from humans, animals, and cultured cells
Localization (mutation) of CRC associated with colorectal cancer
1) Confidence 0.10 Published 2008 Journal PPAR Research Section Body Doc Link PMC2422873 Disease Relevance 1.89 Pain Relevance 0.07
Because of its localization within the Mom-1 (Min modifier) locus, and its promotion of tumors in APCMin mice, it had first been suggested that PLA2G2A may represent a tumor suppressor gene involved in familial forms of CRC [44].
Localization (localization) of CRC associated with cancer and colon cancer
2) Confidence 0.09 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2585099 Disease Relevance 1.13 Pain Relevance 0.06
the cause of CRC.
Localization (cause) of CRC associated with colon cancer
3) Confidence 0.07 Published 2009 Journal PPAR Research Section Body Doc Link PMC2672162 Disease Relevance 0.89 Pain Relevance 0.17
Recent data from HNPCC mutation carriers support the assertion that smoking significantly increases CRC risk in HNPCC mutation carriers (hazard ratio of 1.43, P < 0.04) (68).
Localization (risk) of CRC associated with colorectal cancer and nicotine addiction
4) Confidence 0.06 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1361617 Disease Relevance 0.83 Pain Relevance 0
Therefore, we need novel biomarkers that are non-invasive to enable us to detect CRC quite early.
Localization (detect) of CRC associated with colorectal cancer
5) Confidence 0.05 Published 2010 Journal International Journal of Molecular Sciences Section Abstract Doc Link PMC2956090 Disease Relevance 0.78 Pain Relevance 0
The patient underwent low anterior resection for CRC on 14 July 2004.
Localization (resection) of CRC in anterior associated with colon cancer
6) Confidence 0.04 Published 2008 Journal Cases J Section Body Doc Link PMC2503966 Disease Relevance 1.48 Pain Relevance 0.08

General Comments

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