INT190042
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
To study the role of DC immune in LPS-induced sepsis, a transgenic mouse model with DCs overexpressing a human form of anti-apoptotic protein Bcl-2 (DC-hBcl-2 mice) has been used [28]. | |||||||||||||||
| |||||||||||||||
|
While the expression of the anti-apoptotic molecule Mcl-1 is decreased, that of the pro-apoptotic molecule Bax is increased. | |||||||||||||||
| |||||||||||||||
|
Therefore, prognostic significance of cell cycle regulatory protein such as p53 and cyclin D1 and anti-apoptosis protein, survivin, has been investigated in malignancies [10-13]. | |||||||||||||||
| |||||||||||||||
|
Synthetic hBCL2-BH4 and hBCL2A1-BH4 peptides were both effective in reducing I/R, whereas a peptide from the BH3 domain of Bak, a pro-apoptotic BCL2 family member, was not (Figure 3).
| |||||||||||||||
| |||||||||||||||
|
S4AC), and inhibited the expression of the anti-metastatic protein p53 (P<0.01, Fig. | |||||||||||||||
| |||||||||||||||
|
The proliferative phase is marked by high mitotic index, and Ki-67 indicative of rapid cellular proliferation, as well as elevated levels of BCL2, an anti-apoptotic factor, presumably involved in stabilizing the cells during this period and allowing for normal physiologic growth in preparation for implantation and pregnancy (153). | |||||||||||||||
| |||||||||||||||
|
(RmCD8-2), anti-B220 (TIB146), anti-CCR9 (7E7), and anti-gp38 (8.1.1) antibodies were produced in our laboratory. | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.