INT190044

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Context Info
Confidence 0.32
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.77
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Msh2, Msh6) nuclear chromosome (Msh2) ATPase activity (Msh2)
nucleus (Msh2) enzyme binding (Msh2) cell cycle (Msh2)
Msh2 (Mus musculus)
Msh6 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 3 91.28 High High
cINOD 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 5 87.76 High High
Cancer 116 82.76 Quite High
Mucositis 1 73.28 Quite High
Apoptosis 41 73.04 Quite High
Targeted Disruption 7 71.80 Quite High
Aging 13 70.12 Quite High
Death 6 68.28 Quite High
Diarrhoea 1 67.20 Quite High
Frailty 4 50.00 Quite Low
Nicotine Addiction 3 36.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MSH2–MSH6 can specifically recognize distinct types of damaged DNA (such as those caused by oxidative or alkylating agents).
MSH2 Binding (recognize) of MSH6
1) Confidence 0.32 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1361617 Disease Relevance 0.51 Pain Relevance 0
repair complex) is important for repeat expansion, whereas the Msh6 protein (found in association with Msh2 in the MutS?
Msh2 Binding (association) of Msh6 protein
2) Confidence 0.03 Published 2007 Journal BMC Mol Biol Section Body Doc Link PMC1940261 Disease Relevance 0.27 Pain Relevance 0.05

General Comments

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