INT190057

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TSC1) embryo development (TSC1) protein complex (TSC1)
cytoplasm (TSC1)
TSC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 8 66.32 Quite High
Bioavailability 1 32.40 Quite Low
depression 9 5.00 Very Low Very Low Very Low
antiepileptic Drug 7 5.00 Very Low Very Low Very Low
Lamotrigine 6 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
Migraine 4 5.00 Very Low Very Low Very Low
carbamazepine 4 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 142 100.00 Very High Very High Very High
Hematologic Neoplasms 2 89.08 High High
Myeloid Leukemia 9 87.36 High High
Watson Syndrome 2 85.48 High High
Apoptosis 56 67.36 Quite High
Breast Cancer 6 54.28 Quite High
Toxicity 8 50.00 Quite Low
Leukemia 8 45.96 Quite Low
Glioblastoma 1 38.40 Quite Low
Neurofibroma 1 35.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
mice, presumably by inactivating Nf1 gene expression as a myeloid lineage tumor suppressor gene.
Positive_regulation (inactivating) of Negative_regulation (inactivating) of tumor suppressor associated with cancer
1) Confidence 0.01 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1361617 Disease Relevance 0.83 Pain Relevance 0.03
Epigenetic drugs could particularly target these repressed tumor suppressor genes.
Positive_regulation (target) of Negative_regulation (repressed) of tumor suppressor associated with cancer
2) Confidence 0.01 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2926634 Disease Relevance 0.25 Pain Relevance 0

General Comments

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