INT190086

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Context Info
Confidence 0.47
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.10
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hivep3) intracellular (Hivep3) DNA binding (Hivep3)
cytoplasm (Hivep3)
Anatomy Link Frequency
nerves 2
Hivep3 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 20 98.72 Very High Very High Very High
Neuronal excitability 2 98.48 Very High Very High Very High
nociceptor 2 96.64 Very High Very High Very High
Inflammation 16 95.80 Very High Very High Very High
cytokine 16 93.96 High High
Pain 14 87.52 High High
Neuropathic pain 36 85.92 High High
trigeminal ganglion 20 80.56 Quite High
Spinal cord 26 75.56 Quite High
Peripheral nerve injury 18 69.20 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 18 95.80 Very High Very High Very High
Neuropathic Pain 58 89.80 High High
Nervous System Injury 30 88.72 High High
Pain 14 87.52 High High
Ganglion Cysts 24 79.68 Quite High
Nociception 2 62.52 Quite High
Necrosis 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Peripheral Neuropathy 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We show for the first time that the expression of ZAS3 and its related genes, ZAS1 and ZAS2, is decreased in the ipsilateral versus contralateral L6 DRG seven days after SpNL (Figure 8).
Negative_regulation (decreased) of Gene_expression (expression) of ZAS3
1) Confidence 0.47 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1361774 Disease Relevance 0.73 Pain Relevance 0.85
This study localizes ZAS3 protein expression in neuronal cell bodies of the hippocampus proper and dentate gyrus (Figure 2), which contain groups of nerves that play a crucial role in the mechanisms of learning, emotion and memory.
Negative_regulation (localizes) of Gene_expression (expression) of ZAS3 in nerves associated with hippocampus
2) Confidence 0.34 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1361774 Disease Relevance 0.37 Pain Relevance 0.31

General Comments

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