INT19012

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Context Info
Confidence 0.10
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.44

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plasma membrane (Ghsr, Sstr1) signal transducer activity (Ghsr, Sstr1) cytoplasm (Sstr1)
Ghsr (Rattus norvegicus)
Sstr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opiate 12 100.00 Very High Very High Very High
Somatostatin 8 100.00 Very High Very High Very High
agonist 2 78.32 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Present data indicate that one of the major differences in the actions of dermorphin, 2549, and GHRP is the inhibition of somatostatin (SRIF) release by the opiates but not by GHRP.
GHRP Negative_regulation (inhibition) of Localization (release) of SRIF associated with somatostatin and opiate
1) Confidence 0.10 Published 1991 Journal Endocrinology Section Abstract Doc Link 2004615 Disease Relevance 0 Pain Relevance 0.72
Present data indicate that one of the major differences in the actions of dermorphin, 2549, and GHRP is the inhibition of somatostatin (SRIF) release by the opiates but not by GHRP.
GHRP Negative_regulation (inhibition) of Localization (release) of SRIF associated with somatostatin and opiate
2) Confidence 0.10 Published 1991 Journal Endocrinology Section Abstract Doc Link 2004615 Disease Relevance 0 Pain Relevance 0.72

General Comments

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