INT190128

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.21
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) small molecule metabolic process (CPOX) oxidoreductase activity (CPOX)
plasma membrane (PTGER1) cytoplasm (CPOX) signal transducer activity (PTGER1)
Anatomy Link Frequency
macrophages 3
PTGER1 (Homo sapiens)
CPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 11 97.72 Very High Very High Very High
Pain 18 96.96 Very High Very High Very High
Stimulus evoked pain 2 95.88 Very High Very High Very High
Neuropathic pain 9 83.36 Quite High
Inflammation 16 81.84 Quite High
IPN 5 80.72 Quite High
Hyperalgesia 8 78.72 Quite High
Analgesic 2 74.84 Quite High
Perioperative pain 1 72.16 Quite High
hyperexcitability 1 69.80 Quite High
Disease Link Frequency Relevance Heat
Hypersensitivity 4 95.88 Very High Very High Very High
Neuroma 12 95.84 Very High Very High Very High
Pain 13 95.20 Very High Very High Very High
Neuropathic Pain 15 83.36 Quite High
INFLAMMATION 21 81.84 Quite High
Inflammatory Pain 5 80.72 Quite High
Hyperalgesia 10 78.72 Quite High
Post Operative Pain 1 72.16 Quite High
Nervous System Injury 38 55.20 Quite High
Injury 25 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we report that a rapid increase of EP1 receptor levels in injured human sensory neurones preceded Cox-2 expression in infiltrating macrophages.
Positive_regulation (increase) of EP1 in macrophages Negative_regulation (preceded) of Gene_expression (expression) of Cox in macrophages
1) Confidence 0.04 Published 2006 Journal BMC Neurol Section Body Doc Link PMC1361784 Disease Relevance 1.21 Pain Relevance 1.38

General Comments

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