INT190147

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MMP12, MMP2, MMRN1) peptidase activity (MMP12, MMP2) proteinaceous extracellular matrix (MMP12, MMP2)
extracellular space (MMP2) cell adhesion (MMRN1) plasma membrane (MMP2)
MMP12 (Homo sapiens)
MMP2 (Homo sapiens)
MMRN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 151 100.00 Very High Very High Very High
Inflammation 22 96.40 Very High Very High Very High
cytokine 20 77.36 Quite High
Inflammatory mediators 2 27.44 Quite Low
corticosteroid 8 5.00 Very Low Very Low Very Low
dexamethasone 7 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 96.40 Very High Very High Very High
Airway Remodeling 5 86.08 High High
Nicotine Addiction 1 83.40 Quite High
Respiratory Disease 1 59.76 Quite High
Asthma 12 57.20 Quite High
Pulmonary Disease 16 56.32 Quite High
Targeted Disruption 1 51.04 Quite High
Disease 2 48.24 Quite Low
Emphysema 3 44.56 Quite Low
Cough 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, MMP-12 can activate other MMPs, for example, MMP-2 and -3, leading to subsequent degradation of other ECM proteins [10].
MMP-12 Positive_regulation (activate) of MMP-2 Positive_regulation (leading) of Protein_catabolism (degradation) of ECM associated with metalloproteinase
1) Confidence 0.03 Published 2005 Journal Respir Res Section Body Doc Link PMC1363355 Disease Relevance 0.87 Pain Relevance 0.90

General Comments

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