INT190246

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.41
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TARBP2, PKLR) small molecule metabolic process (PKLR) nucleus (TARBP2)
intracellular (TARBP2) carbohydrate metabolic process (PKLR) cytoplasm (TARBP2)
Anatomy Link Frequency
ADAR 2
TARBP2 (Homo sapiens)
PKLR (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 2 95.34 Very High Very High Very High
Rsd 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Suicidal Behaviour 2 81.72 Quite High
Death 2 68.24 Quite High
Influenza Virus Infection 2 55.00 Quite High
Helminth Infection 28 5.00 Very Low Very Low Very Low
Infection 18 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 12 5.00 Very Low Very Low Very Low
Viral Infection 10 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 8 5.00 Very Low Very Low Very Low
Sprains And Strains 8 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, RNA silencing and IFN response seem to be partially overlapping because, for instance, (i) the double-stranded RNA-specific adenosine deaminase ADAR edits miRNA precursor and is also an effector of the IFN response [118], (ii) some viral products efficiently inhibit both RNA silencing and IFN response by targeting their common elicitor, dsRNA [103], and (iii) the TAR Binding Protein (TRBP), which is a negative regulator of PKR, is an essential component of the RISC [119-121].
TAR Binding Protein Positive_regulation (regulator) of PKR in ADAR associated with adenocard
1) Confidence 0.01 Published 2006 Journal Retrovirology Section Body Doc Link PMC1363733 Disease Relevance 0.20 Pain Relevance 0.05
Interestingly, RNA silencing and IFN response seem to be partially overlapping because, for instance, (i) the double-stranded RNA-specific adenosine deaminase ADAR edits miRNA precursor and is also an effector of the IFN response [118], (ii) some viral products efficiently inhibit both RNA silencing and IFN response by targeting their common elicitor, dsRNA [103], and (iii) the TAR Binding Protein (TRBP), which is a negative regulator of PKR, is an essential component of the RISC [119-121].
TRBP Positive_regulation (regulator) of PKR in ADAR associated with adenocard
2) Confidence 0.01 Published 2006 Journal Retrovirology Section Body Doc Link PMC1363733 Disease Relevance 0.20 Pain Relevance 0.05

General Comments

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