INT190281

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.61
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 2
MIR122 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 32.24 Quite Low
aspirin 7 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Rsd 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis C Virus Infection 4 99.72 Very High Very High Very High
Gastrointestinal Neoplasms 2 92.44 High High
Infection 9 85.40 High High
Hepatocellular Cancer 1 70.80 Quite High
Viral Infection 5 70.56 Quite High
Metastasis 2 15.44 Low Low
Helminth Infection 14 5.00 Very Low Very Low Very Low
Cancer 14 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upregulation of miR-122a expression in mutant APC cells induces a gain of wild type APC function, indicating that miR-122a works downstream of APC and suggests that miR-122a expression is lost or downregulated in APC-driven gastrointestinal cancers.
Positive_regulation (Upregulation) of Gene_expression (expression) of miR-122a associated with gastrointestinal neoplasms
1) Confidence 0.45 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2955614 Disease Relevance 0.16 Pain Relevance 0
They demonstrated that Hepatitis C Virus (HCV) replication requires the expression of the miR-122, an abundant liver-specific miRNA.
Positive_regulation (requires) of Gene_expression (expression) of miR-122 in liver associated with hepatitis c virus infection
2) Confidence 0.02 Published 2006 Journal Retrovirology Section Body Doc Link PMC1363733 Disease Relevance 0.45 Pain Relevance 0

General Comments

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