INT190453

Context Info Confidence 0.05 First Reported 2006 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 3 Disease Relevance 0.07 Pain Relevance 0

nucleoplasm (NR2E3) signal transduction (NR2E3) nucleus (NR2E3)

Anatomy Link Frequency germ cells 1 NR2E3 (Homo sapiens)

Pain Link Frequency Relevance Heat tolerance 3 5.00 cytokine 2 5.00 withdrawal 2 5.00 dexamethasone 2 5.00 anesthesia 1 5.00 Pain 1 5.00 Dismenorea 1 5.00 imagery 1 5.00 Potency 1 5.00 cva 1 5.00

Disease Link Frequency Relevance Heat Obesity 1 65.36 Fever 12 5.00 Stress 5 5.00 Hemorrhage 2 5.00 Dysmenorrhea 1 5.00 Pain 1 5.00 Sprains And Strains 1 5.00 Spontaneous Abortion 1 5.00 Pregnancy Complications 1 5.00 Targeted Disruption 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

1-dependent increase in expression of PRL in ESCs [28] although these cells were not exposed to a decidualization stimulus.

Positive_regulation (increase) of ESCs

1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2945765 Disease Relevance 0 Pain Relevance 0

ESCs, derived from the inner cell mass, and primordial or embryonic germ cells (EGCs), derived from the gonadal ridge, are two examples of pluripotent stem cells.

Positive_regulation (derived) of ESCs in germ cells

2) Confidence 0.03 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1373634 Disease Relevance 0.07 Pain Relevance 0

Curr Opin Struct Biol. 2000, 10, 731–736]), and the core itself cannot have RNR activity.

Positive_regulation (have) of RNR

3) Confidence 0.02 Published 2008 Journal Biol Direct Section Body Doc Link PMC2478661 Disease Relevance 0 Pain Relevance 0

General Comments

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