INT190501

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Context Info
Confidence 0.12
First Reported 2006
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.32
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Apex1) mitochondrion (Apex1) lyase activity (Apex1)
aging (Apex1) endoplasmic reticulum (Apex1) intracellular (Apex1)
Anatomy Link Frequency
canals 1
Apex1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 1 88.32 High High
Inflammatory mediators 15 64.88 Quite High
Inflammatory stimuli 2 55.68 Quite High
Inflammatory response 27 40.96 Quite Low
imagery 1 16.48 Low Low
Inflammation 36 5.00 Very Low Very Low Very Low
cytokine 23 5.00 Very Low Very Low Very Low
vagus nerve 6 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 2 86.40 High High
INFLAMMATION 83 64.48 Quite High
Sepsis 99 58.88 Quite High
Stress 1 32.24 Quite Low
Critical Illness 1 26.96 Quite Low
Apoptosis 11 18.08 Low Low
Infection 18 5.00 Very Low Very Low Very Low
Injury 14 5.00 Very Low Very Low Very Low
Disease 14 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The HMG boxes enable HMGB1 to bind chromosomal DNA and fulfil its nuclear
         functions, including determination of nucleosomal structure and stability, and regulation
         of gene expression (Ref. 49).


Regulation (regulation) of Ref
1) Confidence 0.12 Published 2008 Journal Expert Reviews in Molecular Medicine Section Body Doc Link PMC2586610 Disease Relevance 0.32 Pain Relevance 0.06
In agreement with previous studies [10,25] the preoperative status of the pulp did not appear to affect the behavior of the TAZX apex locator in correlation to the apical extent of root canal filling using both methods of working length determination which disagrees with other previous observation which indicate that the Apex Finder showed higher accuracy in vital canal than in necrotic canals [34].
Spec (appear) Regulation (affect) of TAZX apex locator in canals
2) Confidence 0.00 Published 2006 Journal BMC Oral Health Section Body Doc Link PMC1382221 Disease Relevance 0 Pain Relevance 0.04

General Comments

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