INT190523

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.24
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl2) extracellular region (Cxcl2)
Anatomy Link Frequency
plasma 2
bowel 2
Cxcl2 (Mus musculus)
Pain Link Frequency Relevance Heat
Nicotine 40 99.70 Very High Very High Very High
ischemia 19 96.72 Very High Very High Very High
chemokine 19 92.20 High High
cytokine 60 91.00 High High
Inflammation 82 89.92 High High
Inflammatory stimuli 2 75.36 Quite High
Inflammatory response 7 52.32 Quite High
cva 3 45.16 Quite Low
antagonist 7 18.60 Low Low
agonist 26 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 20 97.44 Very High Very High Very High
Cv Unclassified Under Development 19 96.72 Very High Very High Very High
INFLAMMATION 85 89.92 High High
Injury 81 89.40 High High
Pneumonia 13 83.20 Quite High
Lung Injury 29 50.00 Quite Low
Reperfusion Injury 2 50.00 Quite Low
Hemorrhage 7 45.16 Quite Low
Necrosis 11 5.00 Very Low Very Low Very Low
Adult Respiratory Distress Syndrome 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The local effect of radiotherapy on an exposed segment of small bowel includes early increases in MIP-2 levels, a decrease in CD 45 positive cells over time and increased dose dependent apoptosis.
Negative_regulation (decrease) of Positive_regulation (increases) of MIP-2 in bowel associated with apoptosis
1) Confidence 0.41 Published 2008 Journal BMC Surg Section Body Doc Link PMC2248567 Disease Relevance 0.46 Pain Relevance 0.26
Pre-ischemic treatment of mice with DMPP or nicotine significantly reduced the elevation in plasma MIP-2 caused by liver IR.


Negative_regulation (reduced) of Positive_regulation (elevation) of MIP-2 in plasma associated with nicotine
2) Confidence 0.24 Published 2006 Journal BMC Clin Pathol Section Body Doc Link PMC1382240 Disease Relevance 0.35 Pain Relevance 0.61
The simultaneous administration of PPADS and ATP inhibited the induction of MIP-2 and expression of the IL-6 gene, however not that of TNF-?.
Negative_regulation (inhibited) of Positive_regulation (induction) of MIP-2
3) Confidence 0.19 Published 2008 Journal Respir Res Section Body Doc Link PMC2627837 Disease Relevance 0.42 Pain Relevance 0.29

General Comments

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