INT190614

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Context Info
Confidence 0.63
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
muscle 1
bladder 1
Upk1b (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 84 73.60 Quite High
Inflammatory response 8 5.00 Very Low Very Low Very Low
interstitial cystitis 6 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Overactive Bladder 122 100.00 Very High Very High Very High
Bladder Cancer 10 96.76 Very High Very High Very High
Stress 10 84.88 Quite High
INFLAMMATION 96 73.60 Quite High
Adhesions 2 47.72 Quite Low
Apoptosis 10 43.76 Quite Low
Polycystic Kidney Disease 2 27.16 Quite Low
Targeted Disruption 4 24.32 Low Low
Cancer 20 5.00 Very Low Very Low Very Low
Diabetes Mellitus 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, upk1b gene is highly expressed in normal human urothelium and its mRNA was undetectable or markedly reduced in bladder carcinoma [36].
Gene_expression (expressed) of upk1b in bladder associated with bladder cancer
1) Confidence 0.63 Published 2006 Journal BMC Physiol Section Body Doc Link PMC1382248 Disease Relevance 0.78 Pain Relevance 0.03
In tissues isolated from saline-treated mice the following transcripts were expressed preferentially in the detrusor muscle when compared to the mucosa layer: ctsh, eif4ebp2, gstm1, gsto1, serpina3n, sprr2A, upk1a, and upk1b.
Gene_expression (expressed) of upk1b in muscle associated with overactive bladder
2) Confidence 0.49 Published 2006 Journal BMC Physiol Section Body Doc Link PMC1382248 Disease Relevance 0.51 Pain Relevance 0.07

General Comments

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