INT190681

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Bcl2, Fkbp1a) cytosol (Bcl2, Fkbp1a) isomerase activity (Fkbp1a)
mitochondrion (Bcl2) cell morphogenesis (Bcl2) endoplasmic reticulum (Bcl2)
Bcl2 (Mus musculus)
Fkbp1a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 3 5.00 Very Low Very Low Very Low
pruritus 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 6 100.00 Very High Very High Very High
Carcinoma 2 92.48 High High
Cancer 13 64.60 Quite High
Oral Lichen Planus 19 23.28 Low Low
Skin Cancer 9 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 8 5.00 Very Low Very Low Very Low
Eczema 4 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Lichen 3 5.00 Very Low Very Low Very Low
Mouth Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It should be further noted, that an even more direct link between tacrolimus and Bcl-2 family proteins results of the finding that the tacrolimus-binding protein FKBP 38 blocks apoptosis, binds to Bcl-2 and targets Bcl-2 to the mitochondria [17].


Bcl-2 Binding (binds) of FKBP associated with apoptosis
1) Confidence 0.01 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1386691 Disease Relevance 0.46 Pain Relevance 0

General Comments

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