INT190739

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.13
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adcyap1) extracellular space (Adcyap1) extracellular region (Adcyap1)
transmembrane transport (Scn2a1)
Anatomy Link Frequency
neurons 8
Adcyap1 (Mus musculus)
Scn2a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 64 87.52 High High
addiction 4 85.72 High High
imagery 28 85.08 High High
antagonist 24 76.32 Quite High
agonist 20 74.76 Quite High
tetrodotoxin 8 5.00 Very Low Very Low Very Low
Neuropeptide 8 5.00 Very Low Very Low Very Low
Glutamate receptor 8 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 24 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 12 5.00 Very Low Very Low Very Low
Decapitation 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies have found physiological effects of PACAP on SCN neurons in the nanomolar concentration range [23,44].
PACAP Regulation (effects) of Gene_expression (neurons) of SCN in neurons
1) Confidence 0.13 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0 Pain Relevance 0.15
Thus, the available evidence indicates that the PAC1 receptor is responsible for mediating the effects of PACAP on SCN neurons.
PACAP Regulation (effects) of Gene_expression (neurons) of SCN in neurons
2) Confidence 0.13 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0 Pain Relevance 0.21
PACAP can potentiate NMDA currents in acutely disassociated hamster SCN neurons [23] and we sought to determine if PACAP has the same effect in ventral SCN neurons in mice (Fig. 3).
PACAP Regulation (effect) of Gene_expression (neurons) of SCN in neurons
3) Confidence 0.11 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0 Pain Relevance 0.03
Lower concentrations of PACAP (1 and 0.1 nM, 240 sec) did not alter Ca2+ levels within SCN neurons (data not shown).
PACAP Neg (not) Regulation (alter) of Gene_expression (neurons) of SCN in neurons
4) Confidence 0.10 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox