INT190744

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Context Info
Confidence 0.10
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.08
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adcyap1, Car2) cytosol (Car2) signal transduction (Adcyap1)
lyase activity (Car2) extracellular region (Adcyap1) cytoplasm (Car2)
Anatomy Link Frequency
neurons 2
Adcyap1 (Mus musculus)
Car2 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 48 98.36 Very High Very High Very High
agonist 15 76.36 Quite High
antagonist 18 63.48 Quite High
imagery 21 5.00 Very Low Very Low Very Low
tetrodotoxin 6 5.00 Very Low Very Low Very Low
Neuropeptide 6 5.00 Very Low Very Low Very Low
Glutamate receptor 6 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 18 76.84 Quite High
Decapitation 3 49.84 Quite Low
Disseminated Intravascular Coagulation 9 6.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies in cultured rat SCN neurons have demonstrated that PACAP alone can increase Ca2+ as well as modulate glutamatergic evoked responses [16,17].
PACAP Positive_regulation (increase) of Ca2 in neurons
1) Confidence 0.10 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0 Pain Relevance 0.04
Previous studies have demonstrated that PACAP alone can increase Ca2+ as well as modulate glutamatergic evoked responses in cultured rat SCN neurons [16,17,34].
PACAP Positive_regulation (increase) of Ca2 in neurons
2) Confidence 0.10 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0 Pain Relevance 0.03
Finally, PACAP can increase Ca2+ by itself as well as enhance AMPA- and glutamate -evoked increases in Ca2+ [16,17,34].
PACAP Positive_regulation (increase) of Ca2 associated with glutamate
3) Confidence 0.09 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0.08 Pain Relevance 0.09

General Comments

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