INT190747

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Context Info
Confidence 0.05
First Reported 2006
Last Reported 2006
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkaca) Golgi apparatus (Prkaca) protein complex (Prkaca)
cytoplasm (Prkaca) extracellular space (Adcyap1) signal transduction (Adcyap1)
Adcyap1 (Mus musculus)
Prkaca (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 12 65.92 Quite High
imagery 14 60.68 Quite High
agonist 10 60.20 Quite High
Glutamate 32 7.76 Low Low
tetrodotoxin 4 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 12 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 6 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we examined the hypothesis that PACAP regulates AMPA receptors through an activation of the AC/PKA signalling cascade.
PACAP Spec (examined) Regulation (regulates) of Positive_regulation (activation) of PKA
1) Confidence 0.05 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0 Pain Relevance 0.08
This data suggests that PACAP can modulate AMPA currents through a PAC1 receptor mediated activation of the AC/PKA signalling pathway.


PACAP Regulation (modulate) of Positive_regulation (activation) of PKA
2) Confidence 0.05 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1388226 Disease Relevance 0 Pain Relevance 0.06

General Comments

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