INT190774

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.26
Pain Relevance 1.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Ptgs2) endoplasmic reticulum (Ptgs2) enzyme binding (Ptgs2)
protein complex (Ptgs2) cytoplasm (Ptgs2) lipid binding (Ptgs2)
Il4 (Rattus norvegicus)
Ptgs2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
COX2 1 100.00 Very High Very High Very High
antagonist 3 96.12 Very High Very High Very High
cytokine 17 94.08 High High
Inflammation 13 93.72 High High
Eae 34 91.76 High High
Neuropathic pain 29 91.12 High High
allodynia 8 90.16 High High
Pain 10 86.08 High High
Peripheral nerve injury 2 85.92 High High
bradykinin 1 80.80 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 16 93.72 High High
Inflammatory Pain 1 91.76 High High
Neuropathic Pain 40 91.12 High High
Pain 12 86.08 High High
Nervous System Injury 15 85.92 High High
Nociception 8 67.80 Quite High
Ganglion Cysts 24 51.44 Quite High
Cold Sores 22 50.00 Quite Low
Hypersensitivity 1 25.28 Quite Low
Hyperalgesia 14 12.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-4 directly inhibits the induction of nitric oxide synthase and levels of cyclooxygenase 2, the enzymes responsible for the production of nitric oxide and PGE2, respectively [29].
IL-4 Negative_regulation (inhibits) of Positive_regulation (induction) of cyclooxygenase 2 associated with cox2
1) Confidence 0.06 Published 2006 Journal Mol Pain Section Body Doc Link PMC1395302 Disease Relevance 1.26 Pain Relevance 1.45

General Comments

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