INT190804

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.66
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.70
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tlr2) cytoplasm (Tlr2)
Anatomy Link Frequency
whiskers 1
lung 1
Tlr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 2 98.48 Very High Very High Very High
Inflammation 143 86.56 High High
cytokine 33 85.52 High High
Inflammatory marker 2 80.00 Quite High
Central nervous system 6 76.20 Quite High
Dorsal horn neuron 4 72.64 Quite High
Pain 20 70.56 Quite High
medulla 10 67.08 Quite High
COX-2 inhibitor 1 63.92 Quite High
cINOD 7 31.88 Quite Low
Disease Link Frequency Relevance Heat
Viral Meningitis 64 99.08 Very High Very High Very High
Sprains And Strains 97 93.12 High High
Candida Infection 2 93.08 High High
Infection 71 91.32 High High
Necrosis 7 91.04 High High
Cancer 4 90.68 High High
INFLAMMATION 168 86.56 High High
Cold Sores 122 84.76 Quite High
Lung Injury 13 75.00 Quite High
Viral Infection 4 72.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, the slow induction of Tlr2 and -9 in parallel with the delayed infiltration of Iba1+/ED1+ cells in the whiskers area of DA rats is associated with susceptibility to HSE.
Positive_regulation (induction) of Tlr2 in whiskers associated with viral meningitis
1) Confidence 0.66 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929186 Disease Relevance 0.62 Pain Relevance 0.04
Zymosan is a mycotic equivalent to bacterial LPS in that it is yeast cell wall derivative which activates the Toll-like receptor 2 (TLR2) and the alternate complement pathway [4].
Positive_regulation (activates) of Toll-like receptor 2
2) Confidence 0.64 Published 2006 Journal BMC Urol Section Body Doc Link PMC1395324 Disease Relevance 0.95 Pain Relevance 0.35
Zymosan is a mycotic equivalent to bacterial LPS in that it is yeast cell wall derivative which activates the Toll-like receptor 2 (TLR2) and the alternate complement pathway [4].
Positive_regulation (activates) of TLR2
3) Confidence 0.64 Published 2006 Journal BMC Urol Section Body Doc Link PMC1395324 Disease Relevance 0.96 Pain Relevance 0.35
Low Tlr2 and Tlr9 mRNA expression in the susceptible DA rats
Positive_regulation (Low) of Tlr2
4) Confidence 0.48 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929186 Disease Relevance 0.61 Pain Relevance 0.11
High VT mechanical ventilation for 4 hours was associated with a significant increase of TLR4 but not TLR2, a significant decrease of IRAK3 lung gene expression and protein levels, a significant decrease of I?
Positive_regulation (increase) of TLR2 in lung
5) Confidence 0.20 Published 2010 Journal Respir Res Section Abstract Doc Link PMC2841148 Disease Relevance 0.56 Pain Relevance 0.16
LPS probably acts through specific receptors TLR2 and TLR4; as it has been proved that antagonists of these receptors (purified LPS and lipid A) stimulate basic secretion of cortisol.
Positive_regulation (receptors) of TLR2 associated with antagonist
6) Confidence 0.19 Published 2010 Journal Protoplasma Section Body Doc Link PMC2947012 Disease Relevance 0 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox