INT19083

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 1991
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.65
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (NRG1) extracellular space (NRG1) extracellular region (NRG1)
plasma membrane (NRG1) nucleus (NRG1) embryo development (NRG1)
Anatomy Link Frequency
CPA 1
keratinocyte 1
NRG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 6 81.60 Quite High
Kinase C 5 57.20 Quite High
cINOD 1 9.64 Low Low
cytokine 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Taxol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 9 96.16 Very High Very High Very High
Cancer 19 92.56 High High
Hypertrophy 1 83.16 Quite High
Reprotox - General 1 39 59.40 Quite High
Apoptosis 25 28.28 Quite Low
Hypoxia 3 11.32 Low Low
Colon Cancer 1 10.52 Low Low
INFLAMMATION 1 9.40 Low Low
Metastasis 6 5.00 Very Low Very Low Very Low
Hyperplasia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The stability of GGF (with CPA) was also enhanced; an effect was observable with a 5-fold excess of cyclodextrin and the half-life could be extended by 40-75%.
Positive_regulation (enhanced) of GGF in CPA
1) Confidence 0.20 Published 1994 Journal Pharm. Res. Section Abstract Doc Link 7899230 Disease Relevance 0 Pain Relevance 0.07
Many growth and endocrine factors are able to activate p38 MAP kinase including FGF-1 and -2, keratinocyte-derived growth factor (KGF), IL-6, heparin binding epidermal growth factor (HB-EGF), ATP, vitamin D, and Neu differentiation factor (NDF) [13,25,47,79-81].
Positive_regulation (activate) of Neu differentiation factor in keratinocyte
2) Confidence 0.09 Published 2004 Journal Cell Commun Signal Section Body Doc Link PMC449737 Disease Relevance 0.65 Pain Relevance 0.03
An aminopeptidase inhibitor, amastatin, produced more pronounced inhibitory effects at higher pH and the endopeptidase inhibitors, tripeptides YGG and GGF, are effective even below pH 5.0.
Positive_regulation (effective) of GGF
3) Confidence 0.05 Published 1991 Journal Pharm. Res. Section Abstract Doc Link 2014216 Disease Relevance 0 Pain Relevance 0.37

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox