INT19084

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Context Info
Confidence 0.42
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 4.90
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (NRG1) extracellular space (NRG1) extracellular region (NRG1)
plasma membrane (NRG1) nucleus (NRG1) embryo development (NRG1)
Anatomy Link Frequency
nasal mucosa 1
NRG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 23 99.34 Very High Very High Very High
abdominal pain 4 95.24 Very High Very High Very High
corticosteroid 44 88.64 High High
Enkephalin 5 82.88 Quite High
Antihistamine 28 58.32 Quite High
antagonist 3 52.48 Quite High
cytokine 5 43.04 Quite Low
Bioavailability 3 5.00 Very Low Very Low Very Low
pruritus 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 61 100.00 Very High Very High Very High
Fistula 24 100.00 Very High Very High Very High
Rhinitis 152 99.46 Very High Very High Very High
INFLAMMATION 22 99.34 Very High Very High Very High
Abdominal Pain 4 95.24 Very High Very High Very High
Vomiting 6 94.60 High High
Hypersensitivity 28 93.92 High High
Sneezing 12 50.32 Quite High
Pruritus 12 49.80 Quite Low
Nasal Obstruction 9 49.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Endoscopic repair of GGF was successful intra-operatively in all patients.
Negative_regulation (repair) of GGF associated with fistula
1) Confidence 0.42 Published 2010 Journal Obes Surg Section Abstract Doc Link 20440578 Disease Relevance 1.22 Pain Relevance 0.10
A retrospective review was performed to identify patients in whom symptomatic GGF was repaired endoscopically at our institution between September 2004 and September 2008.
Negative_regulation (repaired) of GGF associated with fistula
2) Confidence 0.42 Published 2010 Journal Obes Surg Section Abstract Doc Link 20440578 Disease Relevance 0.89 Pain Relevance 0.05
The rationale for therapy using glucocorticosteroids can be summarized by their anti-inflammatory action and by their capacity to reduce nasal mucosa hyperreactivity (ARIA 2007).
Negative_regulation (reduce) of ARIA in nasal mucosa associated with asthma and inflammation
3) Confidence 0.22 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504079 Disease Relevance 0.79 Pain Relevance 0.34
An aminopeptidase inhibitor, amastatin, produced more pronounced inhibitory effects at higher pH and the endopeptidase inhibitors, tripeptides YGG and GGF, are effective even below pH 5.0.
Negative_regulation (inhibitors) of GGF
4) Confidence 0.04 Published 1991 Journal Pharm. Res. Section Abstract Doc Link 2014216 Disease Relevance 0 Pain Relevance 0.38
Therefore, Allergic Rhinitis and Its Impact on Asthma (ARIA) published the guidelines for AR and revised them in 2008.9 The points of the ARIA guidelines are as follows: AR is subdivided by symptom duration and the severity of AR, a stepwise therapeutic approach is needed depending on the ARIA classification, and patients with persistent AR should be evaluated for asthma.
Negative_regulation (published) of ARIA associated with asthma and rhinitis
5) Confidence 0.02 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846743 Disease Relevance 1.99 Pain Relevance 0.09

General Comments

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