INT190876

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Context Info
Confidence 0.15
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.43
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (Apoc3) lipid binding (Apoc3) transport (Apoc3)
extracellular space (Apoc3) extracellular region (Apoc3)
Anatomy Link Frequency
plasma 1
fat 1
Apoc3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 87.52 High High
agonist 7 74.32 Quite High
ischemia 1 59.12 Quite High
Inflammatory response 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Weight Gain 4 94.28 High High
INFLAMMATION 16 87.52 High High
Cardiovascular Disease 16 85.60 High High
Body Weight 71 84.92 Quite High
Disorder Of Lipid Metabolism 15 83.92 Quite High
Obesity 133 81.16 Quite High
Cv Unclassified Under Development 1 59.12 Quite High
Atherosclerosis 9 47.76 Quite Low
Hypolipidemia 1 41.64 Quite Low
Disease 3 38.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, sg/sg mice have reduced plasma triglyceride and apo C-III levels

[Raspe et al., 2001].


Negative_regulation (reduced) of C-III in plasma
1) Confidence 0.15 Published 2003 Journal Nuclear Receptor Signaling Section Body Doc Link PMC1402228 Disease Relevance 0.52 Pain Relevance 0.17
target genes, ACOX, HD, and thiolase but also reduced apo C-III mRNA levels compared to a high fat diet alone in both groups of mice.
Negative_regulation (reduced) of C-III in fat
2) Confidence 0.03 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0.92 Pain Relevance 0

General Comments

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