INT190877

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Context Info
Confidence 0.11
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.09
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (Apoc3) lipid binding (Apoc3) transport (Apoc3)
extracellular space (Apoc3) extracellular region (Apoc3)
Apoc3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 75.92 Quite High
ischemia 1 65.36 Quite High
agonist 11 62.72 Quite High
cytokine 2 8.60 Low Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 27 100.00 Very High Very High Very High
Obesity 266 99.32 Very High Very High Very High
INFLAMMATION 17 75.92 Quite High
Cardiovascular Disease 24 74.00 Quite High
Hyperlipidemia 8 66.00 Quite High
Cv Unclassified Under Development 1 65.36 Quite High
Weight Loss 2 62.12 Quite High
Body Weight 142 50.16 Quite High
Hypolipidemia 1 47.88 Quite Low
Atherosclerosis 9 46.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
positively regulates expression of the mouse and human apoC-III genes and in human HepG2 cells ROR-?
Regulation (regulates) of Gene_expression (expression) of apoC-III
1) Confidence 0.11 Published 2003 Journal Nuclear Receptor Signaling Section Body Doc Link PMC1402228 Disease Relevance 0.44 Pain Relevance 0.13
The molecular mechanisms underlying the effects of fenofibrate on obesity and lipid metabolism involve the changes in the expression of apolipoprotein C-III (apo C-III) and ACOX.
Regulation (changes) of Gene_expression (expression) of C-III associated with obesity and disorder of lipid metabolism
2) Confidence 0.05 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0.82 Pain Relevance 0
The molecular mechanisms underlying the effects of fenofibrate on obesity and lipid metabolism involve the changes in the expression of apolipoprotein C-III (apo C-III) and ACOX.
Regulation (changes) of Gene_expression (expression) of C-III associated with obesity and disorder of lipid metabolism
3) Confidence 0.04 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0.82 Pain Relevance 0

General Comments

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