INT19092

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Context Info
Confidence 0.71
First Reported 1991
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 6
Total Number 7
Disease Relevance 4.99
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
granulosa cells 4
follicles 1
inhbb (Xenopus laevis)
Pain Term Frequency Confidence Heat
anesthesia 4 93.08 High High
palliative 2 74.96 Quite High
imagery 1 74.28 Quite High
abdominal pain 7 71.56 Quite High
Disease Term Frequency Confidence Heat
Cancer 67 99.92 Very High Very High Very High
Leydig Cell Tumor 13 99.44 Very High Very High Very High
Endometriosis (extended) 2 98.80 Very High Very High Very High
Mucinous Adenocarcinoma 10 98.18 Very High Very High Very High
Recurrence 34 94.88 High High
Disease 6 86.08 High High
Rupture 8 85.04 High High
Intestinal Obstruction 10 73.20 Quite High
Abdominal Pain 7 71.56 Quite High
Hydronephrosis 4 68.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Follicular inhibin content after 2 h incubation in vitro was more highly correlated with inhibin release by incubated follicles (r = 0.7; p less than 0.001) than with inhibin synthesis by granulosa cells in vitro (0.4; p less than 0.01).
Gene_expression (synthesis) of inhibin in follicles
1) Confidence 0.71 Published 1991 Journal Biol. Reprod. Section Abstract Doc Link 2015365 Disease Relevance 0 Pain Relevance 0
Overall, there was no significant effect of stage of cycle on follicular inhibin content after 2 h incubation in vitro, release of inhibin by follicles incubated in vitro, or synthesis of inhibin by granulosa cells cultured in vitro.
Gene_expression (synthesis) of inhibin in granulosa cells
2) Confidence 0.71 Published 1991 Journal Biol. Reprod. Section Abstract Doc Link 2015365 Disease Relevance 0 Pain Relevance 0
FSH and LH had no effect on the production of either inhibin or estradiol by cultured granulosa cells.
Gene_expression (production) of inhibin in granulosa cells
3) Confidence 0.55 Published 1991 Journal Biol. Reprod. Section Abstract Doc Link 2015365 Disease Relevance 0 Pain Relevance 0
The effect of stage of estrous cycle and follicular maturation on ovarian inhibin production in sheep.
Gene_expression (production) of inhibin
4) Confidence 0.48 Published 1991 Journal Biol. Reprod. Section Title Doc Link 2015365 Disease Relevance 0 Pain Relevance 0.09
Inhibin is produced by granulosa cells, and should be absent in the oophorectomised, post-menopausal female [16].
Neg (absent) Gene_expression (produced) of Inhibin in granulosa cells associated with endometriosis (extended)
5) Confidence 0.09 Published 2004 Journal Int Semin Surg Oncol Section Body Doc Link PMC483034 Disease Relevance 1.49 Pain Relevance 0.07
Inhibin is produced by granulosa cells, and should be absent in the oophorectomised, post-menopausal female [16].
Neg (absent) Gene_expression (absent) of Inhibin in granulosa cells associated with endometriosis (extended)
6) Confidence 0.07 Published 2004 Journal Int Semin Surg Oncol Section Body Doc Link PMC483034 Disease Relevance 1.55 Pain Relevance 0.07
The mucinous adenocarcinoma expressed positivity for CK20, CEA, CDX2 and CK7, and the SLCT component was positive for inhibin expression.
Gene_expression (expression) of inhibin associated with leydig cell tumor and mucinous adenocarcinoma
7) Confidence 0.07 Published 2010 Journal Pathol. Res. Pract. Section Abstract Doc Link 19674851 Disease Relevance 1.96 Pain Relevance 0.11

General Comments

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