INT190961

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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Scn2a1)
Scn2a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 8 99.98 Very High Very High Very High
Glutamate receptor 5 99.74 Very High Very High Very High
agonist 10 96.00 Very High Very High Very High
Glutamate 22 85.04 High High
Neurotransmitter 96 70.76 Quite High
substance P 11 39.96 Quite Low
excitatory amino acid 2 34.04 Quite Low
adenocard 10 12.24 Low Low
Intracerebroventricular 3 7.60 Low Low
gABA 31 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 4 79.88 Quite High
Targeted Disruption 5 68.08 Quite High
Aging 29 40.36 Quite Low
Sleep Disorders 83 5.00 Very Low Very Low Very Low
Cognitive Disorder 22 5.00 Very Low Very Low Very Low
Hypertension 21 5.00 Very Low Very Low Very Low
Obesity 16 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low
Apnoea 10 5.00 Very Low Very Low Very Low
Affective Disorder 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, GluR antagonists block light-induced phase shifts and Fos-induction in the SCN in vivo [56,57].
Negative_regulation (block) of Positive_regulation (induction) of SCN associated with antagonist and glutamate receptor
1) Confidence 0.27 Published 2006 Journal J Circadian Rhythms Section Body Doc Link PMC1402333 Disease Relevance 0.08 Pain Relevance 0.64
Light pulses, which induce smaller phase shifts in old animals than in young, lead to decreased induction of Per1, but not of Per2, in the SCN of old hamsters (Kolker et al., 2003).
Negative_regulation (decreased) of Positive_regulation (induction) of SCN
2) Confidence 0.02 Published 2010 Journal Frontiers in Neurology Section Body Doc Link PMC2995617 Disease Relevance 0.07 Pain Relevance 0

General Comments

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