INT190986

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Context Info
Confidence 0.17
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Per1) protein binding transcription factor activity (Per1) transmembrane transport (Scn2a1)
cytoplasm (Per1) signal transducer activity (Per1)
Per1 (Rattus norvegicus)
Scn2a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neurotransmitter 95 99.58 Very High Very High Very High
antagonist 8 96.64 Very High Very High Very High
Serotonin 5 75.52 Quite High
Raphe 8 73.60 Quite High
gABA 30 69.52 Quite High
Neuropeptide 12 62.72 Quite High
Glutamate 22 52.08 Quite High
substance P 11 45.84 Quite Low
excitatory amino acid 2 41.56 Quite Low
Somatostatin 17 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Disorders 8 43.52 Quite Low
Hypertension 9 5.00 Very Low Very Low Very Low
Affective Disorder 8 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Neuroleptic Malignant Syndrome 5 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Ganglion Cysts 4 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Possible targets for some of the neurotransmitters are the clock genes per1 and per2, which are induced in the SCN by light or by neurotransmitters, at night.
per1 Positive_regulation (induced) of SCN associated with neurotransmitter
1) Confidence 0.17 Published 2006 Journal J Circadian Rhythms Section Body Doc Link PMC1402333 Disease Relevance 0 Pain Relevance 0.74

General Comments

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