INT191048

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Context Info
Confidence 0.69
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2) cell morphogenesis (Bcl2) endoplasmic reticulum (Bcl2)
intracellular (Bcl2) cytoplasm (Bcl2) cell proliferation (Bcl2)
Bcl2 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 19 99.20 Very High Very High Very High
Breast Cancer 21 89.28 High High
Death 4 45.28 Quite Low
Necrosis 1 34.00 Quite Low
Cancer 15 33.64 Quite Low
Splenomegaly 4 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Weight Loss 3 5.00 Very Low Very Low Very Low
Skin Cancer 3 5.00 Very Low Very Low Very Low
Solid Tumor 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several studies indicate that in vitro treatment with taxanes induces phosphorylation and inactivation of the Bcl-2 protein as well as apoptosis [27], which might explain why Bcl-2-transfected cells retained their sensitivity to taxanes in the present experiment.
Positive_regulation (induces) of Phosphorylation (phosphorylation) of Bcl-2 associated with apoptosis
1) Confidence 0.69 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1410745 Disease Relevance 0.44 Pain Relevance 0

General Comments

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