INT191051

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.82
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Sdcbp) cytoplasm (Sdcbp)
Anatomy Link Frequency
MDA-MB-453 4
Sdcbp (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 1 93.36 High High
agonist 11 60.48 Quite High
cINOD 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 135 100.00 Very High Very High Very High
Breast Cancer 118 100.00 Very High Very High Very High
INFLAMMATION 5 93.36 High High
Metastasis 3 80.20 Quite High
Apoptosis 64 76.56 Quite High
Liposarcoma 1 50.48 Quite High
Reprotox - General 1 5 49.20 Quite Low
Necrosis 4 43.88 Quite Low
Colon Cancer 7 29.04 Quite Low
Death 13 23.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of Bcl-2 in determining the chemosensitivity of breast cancer cells was tested in MDA-MB-453 cells expressing low levels of Bcl-2.
Gene_expression (expressing) of MDA-MB-453 in MDA-MB-453 associated with breast cancer
1) Confidence 0.01 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1410745 Disease Relevance 0.44 Pain Relevance 0
is also expressed in the breast tumor derived cancer cell lines MDA-MB-231, MCF-7, SKBR-3, MDA-MB-435, and MDA-MB-453, irrespective of ER, HER2/neu, or p53 status [13,15,16].
Gene_expression (expressed) of MDA-MB-453 in MDA-MB-453 associated with cancer and breast cancer
2) Confidence 0.01 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206732 Disease Relevance 1.04 Pain Relevance 0.08
To determine the effect of Bcl-2 on chemosensitivity, cell proliferation was compared between MDA-MB-453/pZipneo and MDA-MB-453/Bcl-2-1 cells, which were transfected with empty plasmid vector or plasmid vector encoding the bcl-2 gene.
Gene_expression (transfected) of MDA-MB-453 in MDA-MB-453
3) Confidence 0.01 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1410745 Disease Relevance 0.17 Pain Relevance 0
To determine the effect of Bcl-2 on chemosensitivity, cell proliferation was compared between MDA-MB-453/pZipneo and MDA-MB-453/Bcl-2-1 cells, which were transfected with empty plasmid vector or plasmid vector encoding the bcl-2 gene.
Gene_expression (transfected) of MDA-MB-453 in MDA-MB-453
4) Confidence 0.01 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1410745 Disease Relevance 0.17 Pain Relevance 0

General Comments

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