INT19120

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Context Info
Confidence 0.49
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr3a) cytoplasm (Htr3a)
Anatomy Link Frequency
visceral 1
spinal 1
Htr3a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Visceral pain 1 98.42 Very High Very High Very High
agonist 7 97.86 Very High Very High Very High
Serotonin 1 96.64 Very High Very High Very High
intrathecal 2 95.94 Very High Very High Very High
antinociception 3 95.24 Very High Very High Very High
antagonist 1 78.56 Quite High
Potency 1 36.64 Quite Low
Antinociceptive 3 25.00 Low Low
Spinal cord 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

9 99.24 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

1 98.42 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study examined whether the antinociception produced following the intrathecal (i.t.) administration of serotonin (5-hydroxytryptamine, 5-HT) and other 5-HT receptor agonists in a model of visceral pain that utilizes colorectal distension (CRD) as the noxious visceral stimulus is mediated through interaction with spinal 5-HT1, 5-HT2, or 5-HT3 receptor subtypes.
Positive_regulation (mediated) of 5-HT3 in spinal Binding (interaction) of in visceral associated with antinociception, visceral pain, agonist, serotonin and intrathecal
1) Confidence 0.49 Published 1991 Journal Brain Res. Section Abstract Doc Link 2018933 Disease Relevance 0 Pain Relevance 0.59

General Comments

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