INT191244

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Context Info
Confidence 0.12
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.81
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (SAE1) nucleus (SAE1) ligase activity (SAE1)
SAE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 2 93.48 High High
depression 2 82.24 Quite High
potassium channel 4 24.56 Low Low
Calcium channel 2 20.96 Low Low
Somatostatin 22 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
colic 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoglycemia 150 99.64 Very High Very High Very High
Cardiovascular Disease 2 95.84 Very High Very High Very High
Hepatotoxicity 2 93.24 High High
Overdose 16 86.60 High High
Diabetes Mellitus 16 86.48 High High
Depression 2 82.24 Quite High
Obstructive Jaundice 2 81.16 Quite High
Hyponatremia 2 78.08 Quite High
Hypophosphatemia 2 74.56 Quite High
Bartter Syndrome 4 73.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the elderly the clinical presentation of SUA-induced hypoglycaemia may be atypical, and so a high index of suspicion is required; moreover, even shorter acting SUAs can cause hypoglycaemia, especially if renal or hepatic dysfunction is present.
Localization (presentation) of SUA associated with hypoglycemia and hepatotoxicity
1) Confidence 0.12 Published 2005 Journal Crit Care Section Body Doc Link PMC1414034 Disease Relevance 1.46 Pain Relevance 0.05
Hypertonic glucose infusion rapidly corrects hypoglycaemia, but it then acts as a potent secretagogue for SUA-sensitized ?
Localization (secretagogue) of SUA associated with hypoglycemia
2) Confidence 0.12 Published 2005 Journal Crit Care Section Body Doc Link PMC1414034 Disease Relevance 1.34 Pain Relevance 0.04

General Comments

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