INT191339

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Context Info
Confidence 0.19
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.73
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IDO1) small molecule metabolic process (IDO1) oxidoreductase activity (IDO1)
cellular nitrogen compound metabolic process (IDO1)
IDO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 42 90.36 High High
Pain 29 62.00 Quite High
visual analogue scale 10 61.04 Quite High
Pain score 7 55.12 Quite High
Inflammation 13 50.00 Quite Low
c fibre 11 48.56 Quite Low
unmyelinated 6 48.20 Quite Low
TRP channel 3 5.00 Very Low Very Low Very Low
qutenza 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bladder Disease 34 100.00 Very High Very High Very High
Pain 23 62.00 Quite High
INFLAMMATION 17 50.00 Quite Low
Overactive Bladder 26 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Syndrome 5 5.00 Very Low Very Low Very Low
Incontinence 4 5.00 Very Low Very Low Very Low
Thrombosis 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Metabolic Syndrome 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The energy transfer between t-PnA and DOPE-NBD was minimally changed by Indo (Fig. 2B), possibly because the FRET efficiency between the probes was extremely low (?
Spec (possibly) Negative_regulation (low) of Gene_expression (changed) of Indo
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2809093 Disease Relevance 0 Pain Relevance 0
Again, as depicted in Fig. 4D, a contrasting effect Indo was found: increasing concentrations of Indo induced higher turbidity measurements in DPPC suspensions (closed diamonds) and a significant decrease in turbidity of DOPC suspension (open squares).
Negative_regulation (effect) of Gene_expression (found) of Indo
2) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2809093 Disease Relevance 0 Pain Relevance 0.16
Compared to controls, a three- and five-fold increase of TRPM8-immunoreactive axons was seen in IDO and PBS groups respectively.
Negative_regulation (seen) of Gene_expression (groups) of IDO associated with bladder disease
3) Confidence 0.11 Published 2006 Journal BMC Urol Section Body Doc Link PMC1420318 Disease Relevance 0.73 Pain Relevance 0.15

General Comments

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