INT191417

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Context Info
Confidence 0.18
First Reported 2005
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.16
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
mononuclear cells 1
Rf (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 137 100.00 Very High Very High Very High
alcohol 6 92.72 High High
Arthritis 4 91.20 High High
Pain 22 77.72 Quite High
Inflammatory marker 4 33.04 Quite Low
Osteoarthritis 44 17.60 Low Low
Inflammation 18 5.00 Very Low Very Low Very Low
depression 10 5.00 Very Low Very Low Very Low
methotrexate 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 143 100.00 Very High Very High Very High
Anaerobic Bacterial Infections 10 98.70 Very High Very High Very High
Diabetes Mellitus 26 97.92 Very High Very High Very High
Asthma 22 96.88 Very High Very High Very High
Nicotine Addiction 28 82.00 Quite High
Pain 23 77.72 Quite High
Disease 37 75.00 Quite High
Obesity 30 73.12 Quite High
Fatigue 20 47.12 Quite Low
INFLAMMATION 21 33.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic drinkers were significantly less likely to report poor general health or poor physical health than those who were not chronic drinkers, but significantly more likely to report "RF worried tense or anxious" or "RF lack of rest or sleep".


Neg (lack) Localization (report) of RF
1) Confidence 0.18 Published 2006 Journal Health Qual Life Outcomes Section Body Doc Link PMC1431510 Disease Relevance 0.96 Pain Relevance 0.12
Chronic drinkers were significantly less likely to report poor general health or poor physical health than those who were not chronic drinkers, but significantly more likely to report "RF worried tense or anxious" or "RF lack of rest or sleep".


Neg (lack) Localization (report) of RF
2) Confidence 0.18 Published 2006 Journal Health Qual Life Outcomes Section Body Doc Link PMC1431510 Disease Relevance 0.98 Pain Relevance 0.12
Using this method, both anti-CCP IgG and anti-tetanus IgG as well as total IgM and IgG were found to be significantly enriched in RA synovia, whereas the value for RF-IgM did not differ significantly from 1.
Localization (enriched) of RF associated with rheumatoid arthritis and anaerobic bacterial infections
3) Confidence 0.07 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592782 Disease Relevance 0.51 Pain Relevance 0.17
Similarly, dispersed cells from rheumatoid synovia synthesize immunoglobulins [12,13] and RF [13-15], and synovial fluid-derived mononuclear cells secrete anti-CCP antibodies [16].
Localization (secrete) of RF in mononuclear cells
4) Confidence 0.07 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592782 Disease Relevance 0.09 Pain Relevance 0.04
The purpose of this study is to compare the clinical characteristics and treatment patterns of RA according to the presence of RF in Korean patients.
Localization (presence) of RF associated with rheumatoid arthritis
5) Confidence 0.02 Published 2005 Journal Yonsei Medical Journal Section Abstract Doc Link PMC2815829 Disease Relevance 0.62 Pain Relevance 0.27

General Comments

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