INT191483

Context Info Confidence 0.58 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.16

Anatomy Mention Frequency dorsal root 1

Pain Term Frequency Confidence Heat Dorsal horn 18 93.22 primary afferent fibers 6 66.16 spinal dorsal horn 15 50.00 depression 7 50.00 imagery 5 19.28 Spinal cord 6 5.00 intrathecal 2 5.00 gABA 1 5.00 c fibre 8 5.00 substance P 2 5.00

Disease Term Frequency Confidence Heat Depression 7 50.00 Nociception 1 5.00 Pain 5 5.00 Fever 12 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The single current-pulse stimulation of the dorsal root elicits the following optical responses in the dorsal horn [14]: (1) a brief (< 3 ms) and small, almost undetectable, response is evoked at the entry zone of the dorsal root and, occasionally, in the deep dorsal horn by a 0.05-mA current pulse of 0.05 ms duration; (2) by increasing the stimulus intensity to 0.1 mA, an optical response of longer duration (< 100 ms) appears in lamina I extending to the outer part of lamina II, and in lamina III and deeper laminae; (3) additional increases in intensity (> 0.3 mA) and/or duration (> 0.5 ms) lead to the generation of an intense, prolonged (> 200 ms) response in the superficial laminae I-III, most prominently in lamina II.

Gene_expression (generation) of superficial laminae I-III in dorsal root associated with dorsal horn

1) Confidence 0.58 Published 2006 Journal Mol Pain Section Body Doc Link PMC1434724 Disease Relevance 0 Pain Relevance 0.16

General Comments

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