INT191489

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (P2ry2, Trpv1) mitochondrion (P2ry2) aging (P2ry2)
embryo development (P2ry2) lipid metabolic process (Trpv1) signal transducer activity (P2ry2)
Anatomy Link Frequency
dorsal horn 3
P2ry2 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spinal dorsal horn 15 100.00 Very High Very High Very High
qutenza 83 92.12 High High
Dorsal horn 18 67.12 Quite High
depression 7 50.00 Quite Low
addiction 3 37.92 Quite Low
Action potential 14 34.56 Quite Low
Cannabinoid 1 25.44 Quite Low
antagonist 15 5.00 Very Low Very Low Very Low
c fibre 8 5.00 Very Low Very Low Very Low
agonist 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fever 12 77.56 Quite High
Depression 7 50.00 Quite Low
Pain 5 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicate that the threshold for activation of TRPV1 channels in the spinal dorsal horn is decreased by the activation of the P2Y receptor.
Positive_regulation (activation) of P2Y receptor in dorsal horn Negative_regulation (decreased) of Positive_regulation (activation) of TRPV1 in dorsal horn associated with spinal dorsal horn
1) Confidence 0.03 Published 2006 Journal Mol Pain Section Body Doc Link PMC1434724 Disease Relevance 0.08 Pain Relevance 0.44

General Comments

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