INT191542

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Context Info
Confidence 0.22
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.61
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCA3) ATPase activity (ABCA3) plasma membrane (ABCA3)
transmembrane transport (ABCA3)
Anatomy Link Frequency
respiratory 1
ABCA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 9 52.12 Quite High
Inflammation 36 5.00 Very Low Very Low Very Low
fibrosis 22 5.00 Very Low Very Low Very Low
cva 13 5.00 Very Low Very Low Very Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Sicca syndrome 2 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Respiratory Failure 5 100.00 Very High Very High Very High
Interstitial Lung Diseases 143 99.40 Very High Very High Very High
Respiratory Disease 3 98.28 Very High Very High Very High
Body Weight 17 93.48 High High
Respiratory Distress 3 84.12 Quite High
Syndrome 27 79.92 Quite High
Pulmonary Alveolar Proteinosis 13 79.00 Quite High
Cretinism 1 77.92 Quite High
Muscle Hypotonia 1 73.92 Quite High
Chorea 1 73.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recessive mutations in the ABCA3 gene were first attributed to fatal respiratory failure in term neonates but are increasingly being recognized as a cause of ILD in older children and young adults.
ABCA3 Binding (recognized) of in respiratory associated with interstitial lung diseases and respiratory failure
1) Confidence 0.22 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2939531 Disease Relevance 1.52 Pain Relevance 0.03
Our finding of the highest linear correlation (R = 0.949) with LBM not only resolves the problem of sex differences, but is also in line with findings in adults [7].
LBM Spec (finding) Binding (finding) of
2) Confidence 0.15 Published 2006 Journal BMC Pediatr Section Body Doc Link PMC1434736 Disease Relevance 0.09 Pain Relevance 0

General Comments

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