INT191614

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adcyap1) extracellular space (Adcyap1) extracellular region (Adcyap1)
nucleus (Rtcd1) molecular_function (Rtcd1) ligase activity (Rtcd1)
Anatomy Link Frequency
pituitary 1
Adcyap1 (Mus musculus)
Rtcd1 (Mus musculus)
Pain Link Frequency Relevance Heat
headache 1 31.56 Quite Low
dopamine receptor 8 5.00 Very Low Very Low Very Low
Hippocampus 8 5.00 Very Low Very Low Very Low
gABA 7 5.00 Very Low Very Low Very Low
long-term potentiation 5 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Neurobehavioral 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Thalamus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 1 85.44 High High
Watson Syndrome 28 83.68 Quite High
Cognitive Disorder 18 82.56 Quite High
Shock 2 76.40 Quite High
Targeted Disruption 6 50.00 Quite Low
Learning Disorders 2 44.80 Quite Low
Intellectual Impairment 1 40.24 Quite Low
Cleidocranial Dysplasia 1 34.52 Quite Low
Pseudarthrosis 1 33.32 Quite Low
Headache Disorders 1 31.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies in drosophila, cultured murine neurons, and Nf1-/- mouse embryos (E12.5) have shown that neurofibromin is necessary for the activation of adenylyl cyclase by pituitary adenylate cyclase activating peptide (PACAP) [6-9].
pituitary adenylate cyclase activating peptide Positive_regulation (activation) of cyclase in pituitary
1) Confidence 0.01 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1434756 Disease Relevance 0.93 Pain Relevance 0

General Comments

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