INT191615

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Nf1, Flna) nucleus (Nf1, Flna) intracellular (Nf1)
extracellular matrix organization (Nf1) protein complex (Nf1) signal transducer activity (Flna)
Nf1 (Mus musculus)
Flna (Mus musculus)
Pain Link Frequency Relevance Heat
dopamine receptor 8 99.68 Very High Very High Very High
Hippocampus 8 85.84 High High
gABA 7 58.24 Quite High
Neurobehavioral 1 45.24 Quite Low
long-term potentiation 5 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Thalamus 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 3 100.00 Very High Very High Very High
Cognitive Disorder 18 75.00 Quite High
Targeted Disruption 6 75.00 Quite High
Watson Syndrome 28 61.92 Quite High
Learning Disorders 2 49.44 Quite Low
Attention Deficit Hyperactivity Disorder 2 47.92 Quite Low
Shock 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Macrocephaly 1 5.00 Very Low Very Low Very Low
Cleidocranial Dysplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Through this analysis, it is proposed that neurofibromin forms a binding complex with amyloid precursor protein (APP) and through filamin proteins interacts with a dopamine receptor (Drd3).
neurofibromin Binding (interacts) of filamin associated with dopamine receptor and alzheimer's dementia
1) Confidence 0.08 Published 2006 Journal BMC Neurosci Section Abstract Doc Link PMC1434756 Disease Relevance 0.53 Pain Relevance 0.17

General Comments

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