INT191685

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (gr) cytosol (Bag1) mitochondrion (Bag1)
nucleus (Bag1) cytoplasm (Bag1)
Bag1 (Mus musculus)
gr (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 72 97.28 Very High Very High Very High
Chronic pancreatitis 1 83.12 Quite High
corticosteroid 1 50.00 Quite Low
palliative 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 36 99.98 Very High Very High Very High
Pancreatic Cancer 41 84.88 Quite High
Pancreatitis 1 83.12 Quite High
Carcinoma 3 73.40 Quite High
Death 2 66.48 Quite High
Lymphatic System Cancer 2 57.64 Quite High
Skin Cancer 2 57.08 Quite High
Breast Cancer 7 55.28 Quite High
Solid Tumor 5 47.44 Quite Low
Reprotox - General 1 3 46.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, DEX did not up-regulate expression of BAG-1 in our studies, neither basal, nor in the presence of cisplatin, as would have been expected in the case of an anti-apoptotic influence of BAG-1 on GR signaling.
BAG-1 Neg (not) Regulation (influence) of GR associated with apoptosis and dexamethasone
1) Confidence 0.08 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1434760 Disease Relevance 1.10 Pain Relevance 0.21

General Comments

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