INT191687

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Xiap) nucleus (Xiap) intracellular (Xiap)
protein complex (Xiap) ligase activity (Xiap) cytoplasm (Xiap)
Igh-Dex (Mus musculus)
Xiap (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 72 100.00 Very High Very High Very High
corticosteroid 1 50.00 Quite Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 41 99.48 Very High Very High Very High
Apoptosis 36 97.32 Very High Very High Very High
Breast Cancer 7 90.48 High High
Cancer 43 41.04 Quite Low
Reprotox - General 1 3 38.60 Quite Low
Solid Tumor 5 5.00 Very Low Very Low Very Low
Vomiting 4 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During a time kinetic from 24 to 72 h, DEX strongly enhanced the levels of MKP-1, SGK1 and X-IAP, in several pancreatic cancer cell lines examined, while Bcl-2 expression was only marginally increased.
DEX Positive_regulation (enhanced) of Gene_expression (levels) of X-IAP associated with pancreatic cancer and dexamethasone
1) Confidence 0.01 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1434760 Disease Relevance 0.63 Pain Relevance 0.24

General Comments

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