INT191706

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Context Info
Confidence 0.49
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 3.61
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TNNT1)
Anatomy Link Frequency
autonomic 4
Cardiogenic 2
TNNT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 6 94.64 High High
Catecholamine 94 94.44 High High
Angina 11 87.60 High High
Inflammation 12 84.68 Quite High
Dopamine 8 84.64 Quite High
Bioavailability 1 82.56 Quite High
metalloproteinase 6 75.64 Quite High
cytokine 13 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 10 100.00 Very High Very High Very High
Fever 4 100.00 Very High Very High Very High
Cv General 2 Under Development 3 100.00 Very High Very High Very High
Coronary Artery Disease 11 99.52 Very High Very High Very High
Infarction 3 98.68 Very High Very High Very High
Injury 7 98.36 Very High Very High Very High
Mitral Valve Insufficiency 6 98.24 Very High Very High Very High
Left Ventricular Dysfunction 2 97.80 Very High Very High Very High
Reperfusion Injury 1 95.40 Very High Very High Very High
Emergencies 3 95.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Troponin T levels during autonomic instability
Positive_regulation (during) of Gene_expression (levels) of Troponin T in autonomic
1) Confidence 0.49 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1434771 Disease Relevance 0.14 Pain Relevance 0.19
Cardiogenic shock as a complication of acute mitral valve regurgitation following posteromedial papillary muscle infarction in the absence of coronary artery disease

A 48 year old man was transferred to our department with cardiogenic shock, pyrexia, a high white cell count and significant serum troponin T level.

Positive_regulation (transferred) of Gene_expression (transferred) of troponin T in Cardiogenic associated with coronary artery disease, mitral valve insufficiency, cv general 2 under development, fever and infarction
2) Confidence 0.49 Published 2008 Journal J Cardiothorac Surg Section Title Doc Link PMC2586022 Disease Relevance 1.12 Pain Relevance 0
Elevated values of troponin T detected during autonomic instability were not associated with left ventricular dysfunction.
Positive_regulation (values) of Gene_expression (detected) of troponin T in autonomic associated with left ventricular dysfunction
3) Confidence 0.45 Published 2006 Journal J Negat Results Biomed Section Abstract Doc Link PMC1434771 Disease Relevance 0.64 Pain Relevance 0.16
Some authors found that MPO serum levels were equally distributed among patients with low and high Troponin T (TnT) serum levels, which indicates that elevated MPO levels are not temporary related to myocardial injury.47 Moreover, MPO identifies patients at risk for cardiovascular events who have low baseline TnT levels, even before complete microvascular obstruction.
Positive_regulation (elevated) of Gene_expression (levels) of TnT associated with injury and urological neuroanatomy
4) Confidence 0.30 Published 2006 Journal Biomark Insights Section Body Doc Link PMC2716777 Disease Relevance 1.71 Pain Relevance 0.28
None of the data/signals were of sufficient quality to allow heavy-atom finding de novo, but using the partial model BUSTER-TNT phases in SHARP allowed the detection of six Pt sites and one Hg site, and also confirmed (with peaks higher than 3?
Positive_regulation (allowed) of Gene_expression (phases) of BUSTER-TNT
5) Confidence 0.03 Published 2010 Journal Acta Crystallographica Section D: Biological Crystallography Section Body Doc Link PMC2852306 Disease Relevance 0 Pain Relevance 0
None of the data/signals were of sufficient quality to allow heavy-atom finding de novo, but using the partial model BUSTER-TNT phases in SHARP allowed the detection of six Pt sites and one Hg site, and also confirmed (with peaks higher than 3?
Positive_regulation (confirmed) of Gene_expression (phases) of BUSTER-TNT
6) Confidence 0.03 Published 2010 Journal Acta Crystallographica Section D: Biological Crystallography Section Body Doc Link PMC2852306 Disease Relevance 0 Pain Relevance 0

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