INT191732

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Context Info
Confidence 0.28
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 3.60
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
body 1
Lmrq1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 9 77.52 Quite High
Bioavailability 6 75.84 Quite High
headache 3 25.00 Low Low
abdominal pain 1 25.00 Low Low
cytokine 6 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
cryotherapy 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 155 99.96 Very High Very High Very High
Disease 98 99.20 Very High Very High Very High
Leishmaniasis 407 98.12 Very High Very High Very High
Parasitic Infection 6 95.36 Very High Very High Very High
Hypoalbuminemia 1 78.60 Quite High
INFLAMMATION 8 77.52 Quite High
Toxicity 18 68.48 Quite High
Recurrence 14 63.12 Quite High
Bites And Stings 12 58.88 Quite High
Anaemia 3 58.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, given the similar pattern observed in the rodents infected with both Leishmania species we question whether analyses of further parameters could display alterations in the animal from which L. braziliensis was isolated in the necropsy.
Regulation (infected) of Leishmania
1) Confidence 0.28 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2814861 Disease Relevance 0.52 Pain Relevance 0
In this study, we report that under experimental conditions Leishmania parasites can manipulate the feeding behavior of the sand fly to promote its own transmission.
Regulation (manipulate) of Leishmania
2) Confidence 0.25 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1904410 Disease Relevance 0.21 Pain Relevance 0
The mechanism for controlling Leishmania infection to reach a stable self healing process is a balanced immune response.
Regulation (controlling) of Leishmania associated with infection
3) Confidence 0.04 Published 2007 Journal Kinetoplastid Biol Dis Section Abstract Doc Link PMC1868746 Disease Relevance 1.33 Pain Relevance 0
These results authenticate that low stringency, large-scale compound screening combined with computational structure filtering can rapidly expand the chemotypes targeting in vitro and in vivo Leishmania growth and viability.


Regulation (targeting) of Leishmania
4) Confidence 0.03 Published 2009 Journal PLoS Neglected Tropical Diseases Section Abstract Doc Link PMC2765639 Disease Relevance 0.39 Pain Relevance 0.04
The underlying mechanism of the body for controlling Leishmania multiplication and spread, and to achieve a stable self-healing process of lesions is an adequate immune response.
Regulation (controlling) of Leishmania in body
5) Confidence 0.03 Published 2007 Journal Kinetoplastid Biol Dis Section Body Doc Link PMC1868746 Disease Relevance 0.50 Pain Relevance 0.04
Cutaneous Leishmania major has affected many travelers including military personnel in Iraq and Afghanistan.
Regulation (affected) of Leishmania
6) Confidence 0.02 Published 2010 Journal PLoS Neglected Tropical Diseases Section Abstract Doc Link PMC2834752 Disease Relevance 0.33 Pain Relevance 0
The protozoan parasite

Leishmania is responsible for several pathologies collectively known as leishmaniases.

Regulation (responsible) of Leishmania associated with leishmaniasis
7) Confidence 0.01 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1435779 Disease Relevance 0.33 Pain Relevance 0

General Comments

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