INT191805

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Context Info
Confidence 0.58
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.61
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD24) signal transducer activity (CD24)
Anatomy Link Frequency
lymphocyte 1
CD24 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 2 99.52 Very High Very High Very High
cytokine 2 95.12 Very High Very High Very High
Bile 4 90.68 High High
Inflammation 29 80.96 Quite High
agonist 2 50.00 Quite Low
Multiple sclerosis 95 47.80 Quite Low
palliative 4 24.44 Low Low
Arthritis 1 17.40 Low Low
Central nervous system 5 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 56 96.28 Very High Very High Very High
Cholangiocarcinoma 19 89.04 High High
INFLAMMATION 33 80.96 Quite High
Malignant Neoplastic Disease 9 79.56 Quite High
Reprotox - General 1 1 51.32 Quite High
Systemic Lupus Erythematosus 49 48.08 Quite Low
Multiple Sclerosis 102 47.80 Quite Low
Metastasis 5 22.64 Low Low
Benign Prostatic Hypertrophy 13 18.56 Low Low
Arthritis 2 17.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A paired t-test was used to assess the effect of the dinucleotide deletion of P1527 on the allele-specific reduction of CD24 mRNA.
Negative_regulation (reduction) of CD24
1) Confidence 0.58 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1847692 Disease Relevance 0 Pain Relevance 0
For each sample, copy numbers of CD24 mRNA were divided by those of PBGD mRNA to normalize for CD24 mRNA expression and thus avoid sample-to-sample differences in RNA quantity.


Negative_regulation (numbers) of CD24
2) Confidence 0.43 Published 2006 Journal BMC Urol Section Body Doc Link PMC1435920 Disease Relevance 0 Pain Relevance 0
A negative association was suggested between the expression of CD24 and phosphorylated/activated p-MAPK (Kendall¬ís ??
Negative_regulation (/) of CD24
3) Confidence 0.43 Published 2007 Journal J Gastrointest Surg Section Body Doc Link PMC1852393 Disease Relevance 0.38 Pain Relevance 0.10
In addition, several surface molecules, including CD109, CD164 and CD24, were down-regulated as well as chemokine (CXC motif) receptor 4, a chemotactic receptor with a critical role in tumor progression, and TIA1 (TIA cytotoxic granule-associated RNA binding protein), a protein with nucleolytic activity against cytotoxic lymphocyte target cells.
Negative_regulation (regulated) of CD24 in lymphocyte associated with chemokine and cancer
4) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2941452 Disease Relevance 0.23 Pain Relevance 0.22

General Comments

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