INT191811

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 6.00
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD24) signal transducer activity (CD24)
Anatomy Link Frequency
cleavage 2
ovary 1
CD24 (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 380 96.36 Very High Very High Very High
Central nervous system 20 85.00 Quite High
cytokine 9 73.48 Quite High
palliative 7 51.60 Quite High
chemokine 1 50.08 Quite High
Angina 4 46.96 Quite Low
Pain 5 45.28 Quite Low
alcohol 3 43.32 Quite Low
Inflammation 4 5.00 Very Low Very Low Very Low
Bile 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 1 98.56 Very High Very High Very High
Disease 38 98.16 Very High Very High Very High
Prostate Cancer 54 98.04 Very High Very High Very High
Cancer 148 97.98 Very High Very High Very High
Contagious Ecthyma 4 96.44 Very High Very High Very High
Multiple Sclerosis 404 96.36 Very High Very High Very High
Benign Prostatic Hypertrophy 26 95.76 Very High Very High Very High
Cholangiocarcinoma 19 93.36 High High
Malignant Neoplastic Disease 30 92.76 High High
Papillomavirus Infection 19 74.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A CT single nucleotide polymorphism (SNP) at position 170 from the CD24 translation start site (P170) in the CD24 putative cleavage site for the glycosylphosphatidylinositol anchor (?
Regulation (site) of CD24 in cleavage
1) Confidence 0.45 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1847692 Disease Relevance 1.05 Pain Relevance 0.15
A CT single nucleotide polymorphism (SNP) at position 170 from the CD24 translation start site (P170) in the CD24 putative cleavage site for the glycosylphosphatidylinositol anchor (?
Regulation (site) of CD24 in cleavage
2) Confidence 0.45 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1847692 Disease Relevance 1.00 Pain Relevance 0.15
We then tested whether the CD24 genotype affected the time span it took the patients to reach EDSS 6.0 from the day of the first symptom of MS.
Spec (whether) Regulation (affected) of CD24 associated with multiple sclerosis
3) Confidence 0.45 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1847692 Disease Relevance 0.79 Pain Relevance 0.28
They reported CD24 expression and tumor stage as independently predictive of survival on multivariate analysis and suggested membrane-bound CD24 protein as a potential target for immunotherapy.8
Regulation (target) of CD24 associated with cancer
4) Confidence 0.27 Published 2007 Journal J Gastrointest Surg Section Body Doc Link PMC1852393 Disease Relevance 0.76 Pain Relevance 0.05
To test if this polymorphism modulates CD24 mRNA stability, we constructed two plasmids (pTracer CMV2-CD24TG and pTracer CMV2-CD24del; Figure 5, top panel) and transfected Chinese hamster ovary (CHO) cells with the two constructs.
Regulation (modulates) of CD24 in ovary
5) Confidence 0.27 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1847692 Disease Relevance 0 Pain Relevance 0
Thus, a combination of the predictive values of PSA and CD24-mRNA is not useful, at least not on the basis of the present data.
Regulation (values) of CD24-mRNA
6) Confidence 0.27 Published 2006 Journal BMC Urol Section Body Doc Link PMC1435920 Disease Relevance 0.59 Pain Relevance 0
The mean relative CD24 expression value was 0.21 (range 0.013–1.02; median 0.14) in the Pca group and 0.08 (range 0.01–0.29; median 0.06) in the BPH group.
Regulation (value) of CD24 associated with benign prostatic hypertrophy and prostate cancer
7) Confidence 0.27 Published 2006 Journal BMC Urol Section Body Doc Link PMC1435920 Disease Relevance 0.99 Pain Relevance 0
In addition, specific up-regulated genes including CD24, E-cadherin, FABP5, keratins, heat shock protein (27 kDa), and others identified by microarray analysis were also identified by flow cytometry and immunostaining.
Regulation (regulated) of CD24 associated with shock
8) Confidence 0.11 Published 2010 Journal Head Neck Oncol Section Body Doc Link PMC2841166 Disease Relevance 0.82 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox