INT191883

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.68
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) transport (Pbsn) extracellular region (Pbsn)
plasma membrane (Tlr4) intracellular (Tlr4) cytoplasm (Tlr4)
Pbsn (Mus musculus)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 78 100.00 Very High Very High Very High
Inflammation 12 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Calcium channel 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 60 81.56 Quite High
Cancer 12 50.00 Quite Low
Necrosis 9 50.00 Quite Low
Disease 15 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Sepsis 9 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Poisoning 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
by LPS was drastically increased by Pb that reached around 2,000 pg/mL in 1.5 hr.
Pb Positive_regulation (increased) of LPS
1) Confidence 0.03 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1440772 Disease Relevance 0.27 Pain Relevance 0
We examined whether Pb acted through the common PKC and p42/44 MAPK pathway to increase LPS-induced TNF-?
Pb Spec (whether) Positive_regulation (increase) of LPS associated with kinase c
2) Confidence 0.02 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1440772 Disease Relevance 0.13 Pain Relevance 0.08
Pb significantly increased LPS-induced TNF-?
Pb Positive_regulation (increased) of LPS
3) Confidence 0.02 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1440772 Disease Relevance 0.28 Pain Relevance 0

General Comments

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