INT191893

Context Info Confidence 0.03 First Reported 2006 Last Reported 2006 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.13 Pain Relevance 0.05

mitochondrion (Prkca) transport (Pbsn) endoplasmic reticulum (Prkca) enzyme binding (Prkca) protein complex (Prkca) cytoplasm (Prkca)

Pbsn (Mus musculus) Prkca (Mus musculus)

Pain Link Frequency Relevance Heat Kinase C 26 100.00 Inflammation 4 5.00 cytokine 2 5.00 anesthesia 1 5.00 Calcium channel 1 5.00

Disease Link Frequency Relevance Heat Injury 20 66.80 Cancer 4 50.00 Necrosis 3 50.00 Disease 5 5.00 INFLAMMATION 4 5.00 Sepsis 3 5.00 Death 2 5.00 Apoptosis 2 5.00 Infection 2 5.00 Poisoning 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We examined whether Pb acted through the common PKC and p42/44 MAPK pathway to increase LPS-induced TNF-?

Pb Spec (whether) Regulation (acted) of Gene_expression (pathway) of PKC associated with kinase c

1) Confidence 0.03 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1440772 Disease Relevance 0.13 Pain Relevance 0.05

General Comments

This test has worked.