INT191930

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.94
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs1) nuclear envelope (Ptgs1) oxidoreductase activity (Ptgs1)
Golgi apparatus (Ptgs1) endoplasmic reticulum (Ptgs1) plasma membrane (Ptgs1)
Anatomy Link Frequency
neuronal 2
Ptgs1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 13 96.44 Very High Very High Very High
Dopamine 4 91.56 High High
COX-2 inhibitor 19 79.44 Quite High
Inflammatory response 11 66.08 Quite High
cytokine 4 60.20 Quite High
Eae 12 5.00 Very Low Very Low Very Low
dopaminergic neurodegeneration 5 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 13 99.16 Very High Very High Very High
INFLAMMATION 27 96.44 Very High Very High Very High
Parkinson's Disease 108 87.36 High High
Stress 5 82.60 Quite High
Disease 23 66.68 Quite High
Injury 7 59.28 Quite High
Necrosis 2 48.52 Quite Low
Cancer 2 48.16 Quite Low
Targeted Disruption 27 25.40 Quite Low
Drug Induced Neurotoxicity 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To what extent is dopaminergic neuronal death attributable to microglial activation as opposed to a direct effect of cyclooxygenase-mediated reactions?
Negative_regulation (opposed) of Negative_regulation (effect) of cyclooxygenase in neuronal associated with death
1) Confidence 0.07 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1440849 Disease Relevance 0.94 Pain Relevance 0.42

General Comments

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