INT191949

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Context Info
Confidence 0.05
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (NFKB2, NOS2) cytosol (NFKB2, NOS2) nucleus (NFKB2, NOS2)
nucleoplasm (NFKB2) intracellular (NOS2) extracellular matrix organization (NFKB2)
NFKB2 (Homo sapiens)
NOS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 21 98.36 Very High Very High Very High
Arthritis 14 88.80 High High
Inflammatory response 3 82.80 Quite High
rheumatoid arthritis 2 25.12 Quite Low
Bile 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 27 99.04 Very High Very High Very High
INFLAMMATION 23 98.36 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 74.96 Quite High
Necrosis 1 72.48 Quite High
Cancer 1 72.12 Quite High
Hypersensitivity 1 55.08 Quite High
Experimental Arthritis 1 34.12 Quite Low
Rheumatoid Arthritis 2 25.12 Quite Low
Protozoal Infection 2 5.00 Very Low Very Low Very Low
Giardiasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
They inhibit NFkB, a transcription factor which stimulates iNOS, an inducible enzyme which produces the inflammatory agent nitric oxide.
NFkB Positive_regulation (stimulates) of iNOS associated with inflammation
1) Confidence 0.05 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1440857 Disease Relevance 1.16 Pain Relevance 0.31

General Comments

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