INT191973

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 13
Total Number 13
Disease Relevance 1.84
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Sit1)
Anatomy Link Frequency
blood 8
intestine 1
Sit1 (Mus musculus)
Pain Link Frequency Relevance Heat
Parenteral administration 12 76.64 Quite High
vagus nerve 12 70.08 Quite High
abdominal pain 12 41.20 Quite Low
peripheral neuropathy 12 36.08 Quite Low
Inflammation 13 7.28 Low Low
corticosteroid 7 5.00 Very Low Very Low Very Low
Antihistamine 5 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoglycemia 24 91.56 High High
Diabetes Mellitus 216 89.64 High High
Hypersensitivity 6 80.88 Quite High
Diarrhoea 24 53.72 Quite High
Disease 2 53.20 Quite High
Constipation 24 43.12 Quite Low
Fecal Incontinence 12 42.44 Quite Low
Abdominal Pain 12 41.20 Quite Low
Gastric Motility Disorder 12 40.56 Quite Low
Peripheral Neuropathy 12 36.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The SIT was expressed as percentage (%) of the distance travelled by the charcoal meal to length of the intestine.
Gene_expression (expressed) of SIT in intestine
1) Confidence 0.44 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0 Pain Relevance 0
Furthermore, no significant correlation was detected between SIT-induced modifications in allergen-specific IgG4 antibodies and AMP responsiveness.
Neg (no) Gene_expression (detected) of SIT
2) Confidence 0.39 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2949816 Disease Relevance 0.13 Pain Relevance 0
Charcoal meal was administered (i.g) 30 min after insulin administration and SIT was determined after 50 min.
Gene_expression (administration) of SIT
3) Confidence 0.38 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0.12 Pain Relevance 0
While insulin in all the doses tested produced similar degree of acceleration of SIT, the effect on serum insulin levels was noticed to be dose related.


Gene_expression (produced) of SIT
4) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0 Pain Relevance 0.04
and 2 m U/kg) but produced a significant acceleration of SIT.
Gene_expression (produced) of SIT
5) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0 Pain Relevance 0.06
and 2 m U/kg) produced significant acceleration of SIT and were associated with normal blood glucose levels.
Gene_expression (produced) of SIT in blood
6) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0.07 Pain Relevance 0
However, the higher dose (2 U/kg) produced an acceleration of SIT that was associated with a profound fall in blood glucose levels (P < 0.01).
Gene_expression (produced) of SIT in blood
7) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0.14 Pain Relevance 0
and 2 m U/kg) did not alter blood glucose levels significantly but produced a significant acceleration of SIT (P < 0.01) (Table 1).
Gene_expression (produced) of SIT in blood
8) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0.26 Pain Relevance 0
However, the higher dose of insulin (2 U/kg) produced an acceleration of SIT that was associated with a significant fall in blood glucose levels (P < 0.01) (Fig 2).
Gene_expression (produced) of SIT in blood
9) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0 Pain Relevance 0.07
and 2 m U/kg) produced significant acceleration of SIT and were associated with normal blood glucose levels.
Gene_expression (produced) of SIT in blood
10) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Abstract Doc Link PMC1444921 Disease Relevance 0.39 Pain Relevance 0
However the higher dose of insulin (2 U/kg) produced an acceleration of SIT that was associated with a significant fall in blood glucose levels (P < 0.01) (Fig 2).


Gene_expression (produced) of SIT in blood
11) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1444921 Disease Relevance 0.06 Pain Relevance 0
However, the highest dose of insulin (2 U/kg) produced an acceleration of SIT that was associated with significant fall in blood glucose levels.
Gene_expression (produced) of SIT in blood
12) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Abstract Doc Link PMC1444921 Disease Relevance 0.36 Pain Relevance 0
Insulin at the lowest dose produced an acceleratory effect on SIT that was independent of blood glucose and serum insulin levels in normal mice.



Gene_expression (produced) of SIT in blood
13) Confidence 0.34 Published 2006 Journal BMC Pharmacol Section Abstract Doc Link PMC1444921 Disease Relevance 0.31 Pain Relevance 0

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