INT192012

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.30
First Reported 2006
Last Reported 2010
Negated 0
Speculated 3
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 3.61
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (RYR2) transmembrane transport (RYR2)
Anatomy Link Frequency
reticulum 1
RYR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 3 90.96 High High
imagery 21 50.00 Quite Low
Angina 5 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 77 99.32 Very High Very High Very High
Arrhythmogenic Right Ventricular Dysplasia 139 98.56 Very High Very High Very High
Syndrome 4 92.68 High High
Heart Rate Under Development 26 92.32 High High
Shock 1 91.32 High High
Cleidocranial Dysplasia 4 86.40 High High
Adhesions 15 84.16 Quite High
Apoptosis 15 80.40 Quite High
Cardiomyopathy 13 79.28 Quite High
Congenital Anomalies 15 79.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The association of a SNP in RYR2 with exercise heart rate responses in multiple analyses is quite consistent with the fundamental role of the ryanodine receptor on the sarcoplasmic reticulum in calcium trafficking during cardiac muscle excitation-contraction coupling [57].
RYR2 Spec (analyses) Binding (association) of in reticulum
1) Confidence 0.30 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC1995617 Disease Relevance 0.17 Pain Relevance 0
3 have been found in association with one of the three families linked to the ARVC2 locus, and in one isolated case of ARVC [5].
ARVC2 Binding (linked) of associated with arrhythmogenic right ventricular dysplasia
2) Confidence 0.13 Published 2006 Journal BMC Med Genet Section Body Doc Link PMC1444927 Disease Relevance 1.14 Pain Relevance 0.05
We report a South African family with ARVC segregating as an autosomal dominant trait for which we obtained lod scores highly suggestive of linkage to the ARVC6 locus on chromosome 10p12-p14 [27].
ARVC6 Spec (suggestive) Binding (linkage) of associated with arrhythmogenic right ventricular dysplasia
3) Confidence 0.12 Published 2006 Journal BMC Med Genet Section Body Doc Link PMC1444927 Disease Relevance 0.58 Pain Relevance 0
Genetic linkage and haplotype analysis provided lod scores that are highly suggestive of linkage to the ARVC6 locus on chromosome 10p12-p14, and the narrowing of the critical region to ~2.9 Mb.
ARVC6 Spec (suggestive) Binding (linkage) of
4) Confidence 0.12 Published 2006 Journal BMC Med Genet Section Abstract Doc Link PMC1444927 Disease Relevance 0.86 Pain Relevance 0
ARVC/D is now recognized to be a genetic disease affecting the desmosomes that are responsible for cell-to-cell binding with mutations eventually affecting gap junction functioning [2].
ARVC Binding (recognized) of associated with disease
5) Confidence 0.01 Published 2010 Journal Indian Pacing and Electrophysiology Journal Section Body Doc Link PMC3009986 Disease Relevance 0.86 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox